ABBV-744
M9218
CAS Number2138861-99-9
Product group Chemicals
Molecular Weight491.55
Overview
- SupplierAbMole BioScience
- Product NameABBV-744
- Delivery Days Customer9
- CAS Number2138861-99-9
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC28H30FN3O4
- Molecular Weight491.55
- Scientific DescriptionABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of the BET family of proteins with IC50 values of 4-18 nM for BRD2, BRD3, BRD4, and BRDT for AML and metastatic desmoplasia-resistant prostate cancer.
- SMILESCCNC(=O)C1=CC2=C([NH]1)C(=O)N(C)C=C2C3=C(OC4=C(C)C=C(F)C=C4C)C=CC(=C3)C(C)(C)O
- UNSPSC12352200