Bio-Connect

ABCB7 Polyclonal Antibody

RD81875A
Reddot Biotech
TargetABCB7
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    ABCB7 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Concentration
    1 mg/ml
  • Gene ID22
  • Target name
    ABCB7
  • Target description
    ATP binding cassette subfamily B member 7
  • Target synonyms
    ABC transporter 7 protein; ABC7; ASAT; Atm1p; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; EST140535; iron-sulfur clusters transporter ABCB7, mitochondrial
  • Scientific Description
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203