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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA579827(ABCC1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA579827(ABCC1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA579827(ABCC1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)

ABCC1 Antibody

CSB-PA579827
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetABCC1
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Overview

  • Supplier
    Cusabio
  • Product Name
    ABCC1 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4363
  • Target name
    ABCC1
  • Target description
    ATP binding cassette subfamily C member 1 (ABCC1 blood group)
  • Target synonyms
    ABC29, ABCC, DFNA77, GS-X, MRP, MRP1, multidrug resistance-associated protein 1, ATP-binding cassette transporter variant ABCC1delta-ex13&14, ATP-binding cassette transporter variant ABCC1delta-ex25&26, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, LTC4 transporter, glutathione S-conjugate export pump, glutathione-S-conjugate-translocating ATPase ABCC1, leukotriene C(4) transporter
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP33527
  • Protein Name
    Multidrug resistance-associated protein 1
  • Scientific Description
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

FAQ

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Figure 1. Western blot analysis of MRP1/ABCC1 using anti-MRP1/ABCC1 antibody (A00872-1). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human PANC-1 whole cell lysates, Lane 2: human A549 whole cell lysates, Lane 3: human HepG2 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-MRP1/ABCC1 antigen affinity purified polyclonal antibody (Catalog # A00872-1) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for MRP1/ABCC1 at approximately 220 kDa. The expected band size for MRP1/ABCC1 is at 220 kDa.
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