ACADVL antibody [N1C1]
GTX114232
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetACADVL
Overview
- SupplierGeneTex
- Product NameACADVL antibody [N1C1]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID37
- Target nameACADVL
- Target descriptionacyl-CoA dehydrogenase very long chain
- Target synonymsACAD6, LCACD, VLCAD, very long-chain specific acyl-CoA dehydrogenase, mitochondrial, acyl-Coenzyme A dehydrogenase, very long chain
- HostRabbit
- IsotypeIgG
- Protein IDP49748
- Protein NameVery long-chain specific acyl-CoA dehydrogenase, mitochondrial
- Scientific DescriptionThe protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tong D, Schiattarella GG, Jiang N, et al. NAD(+) Repletion Reverses Heart Failure With Preserved Ejection Fraction. Circ Res. 2021,128(11):1629-1641. doi: 10.1161/CIRCRESAHA.120.317046Read this paper
- Raimo S, Zura-Miller G, Fezelinia H, et al. Mitochondrial morphology, bioenergetics and proteomic responses in fatty acid oxidation disorders. Redox Biol. 2021,41:101923. doi: 10.1016/j.redox.2021.101923Read this paper
- Chu H, Wu C, Zhao Q, et al. Quantitative proteomics identifies FOLR1 to drive sorafenib resistance via activating autophagy in hepatocellular carcinoma cells. Carcinogenesis. 2021,42(5):753-761. doi: 10.1093/carcin/bgab019Read this paper
- Tenopoulou M, Doulias PT, Nakamoto K, et al. Oral nitrite restores age-dependent phenotypes in eNOS-null mice. JCI Insight. 2018,3(16):pii: 122156. doi: 10.1172/jci.insight.122156.Read this paper
- Stein CS, Jadiya P, Zhang X, et al. Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency. Cell Rep. 2018,23(13):3710-3720.e8. doi: 10.1016/j.celrep.2018.06.002Read this paper
- Tenopoulou M, Chen J, Bastin J, et al. Strategies for correcting very long chain acyl-CoA dehydrogenase deficiency. J Biol Chem. 2015,290(16):10486-94. doi: 10.1074/jbc.M114.635102Read this paper
- Doulias PT, Tenopoulou M, Greene JL, et al. Nitric oxide regulates mitochondrial fatty acid metabolism through reversible protein S-nitrosylation. Sci Signal. 2013,6(256):rs1. doi: 10.1126/scisignal.2003252Read this paper
Datasheet
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