ACBI1

MedChem Express

ACBI1 [2375564-55-7]

5

2375564-55-7

Research Use Only

99.92

C49H58FN9O7S

936.10

ACBI1 is a potent and cooperative SMARCA2 , SMARCA4 and PBRM1 degrader with DC 50 s of 6, 11 and 32 nM, respectively. ACBI1 is a PROTAC degrader. ACBI1 shows anti-proliferative activity. ACBI1 induces apoptosis [1] .

CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)C)NC(C4(CC4)F)=O)=O)=O)C(OCCOC5=CC=C(CN6CCN(C7=CC(C8=C(O)C=CC=C8)=NN=C7N)CC6)C=C5)=C2

-20°C

12352200