Acetyl-CoA Carboxylase 1 antibody [RM232]

GeneTex

Acetyl-CoA Carboxylase 1 antibody [RM232]

9

WB: 1:1000 - 1:2000. IHC-P: 1:300 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

RM232

Unconjugated

ACACA

acetyl-CoA carboxylase alpha

ACAC; ACACAD; ACC; ACC1; ACCA; ACC-alpha; acetyl-CoA carboxylase 1; acetyl-Coenzyme A carboxylase alpha

Rabbit

IgG

Acetyl-CoA carboxylase 1

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5 sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203