IP analysis of solubilied COS1 cells expressing constitutively active ACK1 (250microl) using GTX14776 ACK1 antibody.
IP analysis of solubilied COS1 cells expressing constitutively active ACK1 (250microl) using GTX14776 ACK1 antibody.
ACK1 antibody
GTX14776
ApplicationsImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTNK2
Overview
- SupplierGeneTex
- Product NameACK1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500. IP: 1:200. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.59-0.68 mg/ml
- ConjugateUnconjugated
- Gene ID10188
- Target nameTNK2
- Target descriptiontyrosine kinase non receptor 2
- Target synonymsACK; ACK1; ACK-1; activated CDC42 kinase 1; activated Cdc42-associated kinase 1; activated p21cdc42Hs kinase; p21cdc42Hs; tyrosine kinase non-receptor protein 2
- HostRabbit
- IsotypeIgG
- Protein IDQ07912
- Protein NameActivated CDC42 kinase 1
- Scientific DescriptionThis gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203