ACP-5862 [2230757-47-6]

TargetMol Chemicals

ACP-5862 [2230757-47-6]

72

2230757-47-6

Research Use Only

ACP-5862

C26H23N7O3

481.51

ACP-5862 is a major active and pyrrolidine ring-opened metabolite of Acalabrutinib (IC50: 5.0 nM for BTK). Acalabrutinib is an irreversible and highly selective BTK inhibitor (IC50: 3 nM; EC50: 8 nM).

3 years

CC#CC(=O)NCCCC(=O)c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12

-20°C

12352200