Actinonin

MedChem Express

Actinonin [13434-13-4]

10

13434-13-4

Research Use Only

98.61

C19H35N3O5

385.50

Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces . Actinonin inhibits aminopeptidase M , aminopeptidase N and leucine aminopeptidase . Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a K i of 0.28 nM. Actinonin also inhibits MMP-1 , MMP-3 , MMP-8 , MMP-9 , and hmeprin alpha with K i values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities [1] [2] [3] [4] [5] .

O=C(N[C@H](C(N1[C@H](CO)CCC1)=O)C(C)C)[C@H](CCCCC)CC(NO)=O

-20°C

12352200