Activin Receptor Type IIA antibody [6J16]

GeneTex

Activin Receptor Type IIA antibody [6J16]

9

This antibody was selected for its ability to detect human Activin Receptor type IIA. No cross reactivity was found to Activin RI and RIIB

WB: 1:100 - 1:1000. IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

6J16

200 ug/ml

Unconjugated

ACVR2A

activin A receptor type 2A

activin A receptor, type IIA; activin receptor type-2A; ACTRII; ACVR2

Mouse

IgG2

Activin receptor type-2A

This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]

Human

-20°C or -80°C,2°C to 8°C

12352203