
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA055681(ACVR2A Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
ACVR2A Antibody
CSB-PA055681
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetACVR2A
Overview
- SupplierCusabio
- Product NameACVR2A Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID92
- Target nameACVR2A
- Target descriptionactivin A receptor type 2A
- Target synonymsACTRII, ACVR2, activin receptor type-2A, activin A receptor, type IIA
- HostRabbit
- IsotypeIgG
- Protein IDP27037
- Protein NameActivin receptor type-2A
- Scientific DescriptionThis gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC41116161







