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ADAM10 antibody [N2C1], Internal

GTX104940
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human, Mouse
TargetADAM10
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Overview

  • Supplier
    GeneTex
  • Product Name
    ADAM10 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.65 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID102
  • Target name
    ADAM10
  • Target description
    ADAM metallopeptidase domain 10
  • Target synonyms
    a disintegrin and metalloprotease domain 10; AD10; AD18; CD156c; CDw156; disintegrin and metalloproteinase domain-containing protein 10; HsT18717; kuz; kuzbanian protein homolog; MADM; mammalian disintegrin-metalloprotease; RAK
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO14672
  • Protein Name
    Disintegrin and metalloproteinase domain-containing protein 10
  • Scientific Description
    Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. [provided by RefSeq]
  • Reactivity
    Drosophila, Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mechanisms of Senescence-Related NKG2D Ligands Release and Immune Escape Induced by Chemotherapy in Neuroblastoma Cells. Zhang Y et al., 2022, Front Cell Dev Biol
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  • Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins. Groot AJ et al., 2014 Aug, Mol Cell Biol
    Read more