ADAM15 Antibody

Aviva Systems Biology

ADAM15 Antibody

23

WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200

Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Liquid

ADAM15

ADAM metallopeptidase domain 15

MDC15, disintegrin and metalloproteinase domain-containing protein 15, MDC-15, a disintegrin and metalloproteinase domain 15 (metargidin), metalloprotease RGD disintegrin protein, metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15

Rabbit

IgG

Disintegrin and metalloproteinase domain-containing protein 15

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Human, Mouse, Rat

-20°C

41116161