Adezmapimod
HY-10256
Overview
- SupplierMedChem Express
- Product NameAdezmapimod [152121-47-6]
- Delivery Days Customer10
- CAS Number152121-47-6
- CertificationResearch Use Only
- Estimated Purity99.96
- Molecular FormulaC21H16FN3OS
- Molecular Weight377.43
- Scientific DescriptionAdezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC 50 s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38beta2 , respectively. Adezmapimod inhibits LCK, GSK3beta and PKBalpha with IC 50 s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod does not disrupt JNK activity and is an autophagy and mitophagy activator [1] .
- SMILESO=S(C1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1)C
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200