Adezmapimod (SB203580)
M1781
CAS Number152121-47-6
Product group Chemicals
Estimated Purity0.9997
Molecular Weight377.43
Overview
- SupplierAbMole BioScience
- Product NameAdezmapimod (SB203580)
- Delivery Days Customer9
- CAS Number152121-47-6
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity0.9997
- Molecular FormulaC21H16FN3OS
- Molecular Weight377.43
- Scientific DescriptionAdezmapimod (SB203580) is a P38 MAPK inhibitor with an IC50 of 0.3-0.5 uM, which is 10 times less selective than SAPK3(106T) and SAPK4(106T), and inhibits PKB phosphorylation with an IC50 of 3-5 uM.
- SMILESC[S](=O)C1=CC=C(C=C1)C2=NC(=C([NH]2)C3=CC=NC=C3)C4=CC=C(F)C=C4
- UNSPSC12352200