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Western blot analysis of extracts from NIH-3T3 cells, using GRK2 (Ab-86) antibody.
Western blot analysis of extracts from NIH-3T3 cells, using GRK2 (Ab-86) antibody.
Western blot analysis of extracts from NIH-3T3 cells, using GRK2 (Ab-86) antibody.

ADRBK1 (Ab-86) Antibody

CSB-PA122053
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGRK2
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Overview

  • Supplier
    Cusabio
  • Product Name
    ADRBK1 (Ab-86) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID156
  • Target name
    GRK2
  • Target description
    G protein-coupled receptor kinase 2
  • Target synonyms
    ADRBK1; adrenergic beta receptor kinase 1; BARK1; beta-adrenergic receptor kinase 1; BETA-ARK1; beta-ARK-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP25098
  • Protein Name
    Beta-adrenergic receptor kinase 1
  • Scientific Description
    Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Benovic J.L., FEBS Lett. 283:122-126(1991). Chuang T.T., J. Biol. Chem. 267:6886-6892(1992). Penn R.B., J. Biol. Chem. 269:14924-14930(1994).
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203