FACS analysis of HEK293T cells transfected with either ADSL plasmid(Red) or empty vector control plasmid(Blue) using GTX84956 ADSL antibody [2D10].
![WB analysis of HEK293T cells transfected with ADSL plasmid (Right) or empty vector (Left) for 48 hrs using GTX84956 ADSL antibody [2D10]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_4740_WB_w_23061420_958.webp "WB analysis of HEK293T cells transfected with ADSL plasmid (Right) or empty vector (Left) for 48 hrs using GTX84956 ADSL antibody [2D10]. Loading : 5 ug per lane")
![IHC-P analysis of human prostate carcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_3283_IHC-P_w_23061420_565.webp "IHC-P analysis of human prostate carcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human kidney carcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_3281_IHC-P_w_23061420_246.webp "IHC-P analysis of human kidney carcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human endometrium adenocarcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_3278_IHC-P_w_23061420_694.webp "IHC-P analysis of human endometrium adenocarcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human bladder carcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_3280_IHC-P_w_23061420_698.webp "IHC-P analysis of human bladder carcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human lung carcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_3282_IHC-P_w_23061420_579.webp "IHC-P analysis of human lung carcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human liver tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_3285_IHC-P_w_23061420_649.webp "IHC-P analysis of human liver tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human lymphoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_3286_IHC-P_w_23061420_934.webp "IHC-P analysis of human lymphoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human ovary adenocarcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84956/GTX84956_3279_IHC-P_w_23061420_849.webp "IHC-P analysis of human ovary adenocarcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
FACS analysis of HEK293T cells transfected with either ADSL plasmid(Red) or empty vector control plasmid(Blue) using GTX84956 ADSL antibody [2D10].
ADSL antibody [2D10]
GTX84956
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Monkey, Rat
TargetADSL
Overview
- SupplierGeneTex
- Product NameADSL antibody [2D10]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. IHC-P: 1:150. FCM: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2D10
- Concentration0.55 mg/ml
- ConjugateUnconjugated
- Gene ID158
- Target nameADSL
- Target descriptionadenylosuccinate lyase
- Target synonymsAMPS, ASASE, ASL, adenylosuccinate lyase, adenylosuccinase
- HostMouse
- IsotypeIgG1
- Protein IDP30566
- Protein NameAdenylosuccinate lyase
- Scientific DescriptionAdenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityCanine, Human, Monkey, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism. Zhou Q et al., 2020 Aug 3, J Exp MedRead this paper
- UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism. Feng X et al., 2020 Mar 2, EMBO JRead this paper
Datasheet
Related products
Product group Antibodies
ADSL AntibodyCSB-PA001397ESR2HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
ReactivityHuman, Mouse
TargetADSL
- SizePrice
Product group Antibodies
Anti-ADSL Antibody144-06278
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot
ReactivityHuman, Mouse, Rat
TargetADSL
- SizePrice
Product group Antibodies
Anti-ADSL AntibodyA31262
ApplicationsWestern Blot, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
- SizePrice
Product group Antibodies
Anti-ADSL AntibodyHPA000525
ApplicationsWestern Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
ReactivityHuman
TargetADSL
- SizePrice
Product group Antibodies
ADSL / Adenylosuccinate Lyase AntibodyLS-C334610
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetADSL
- SizePrice
![ADSL antibody [N3C3] detects ADSL protein at cytosol on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. ADSL antibody [N3C3] (GTX114243) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min](https://www.genetex.com/upload/website/prouct_img/normal/GTX114243/GTX114243_40156_IHC_M_w_23060501_181.webp)
Product group Antibodies
ADSL antibody [N3C3]GTX114243
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
ReactivityHuman, Mouse
TargetADSL
- SizePrice
Product group Antibodies
ADSL antibody [AT16C10]GTX57653
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
ReactivityHuman
TargetADSL
- SizePrice
Product group Antibodies
Anti-ADSLY058836
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
ReactivityHuman
- SizePrice
Product group Antibodies
ADSL antibodyGTX30029
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
ReactivityHuman
TargetADSL
- SizePrice