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IHC-P analysis of human endometrium adenocarcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
IHC-P analysis of human endometrium adenocarcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
IHC-P analysis of human endometrium adenocarcinoma tissue using GTX84956 ADSL antibody [2D10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.

ADSL antibody [2D10]

GTX84956
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Monkey, Rat
TargetADSL
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Overview

  • Supplier
    GeneTex
  • Product Name
    ADSL antibody [2D10] - Overexpression Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:2000. IHC-P: 1:150. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    2D10
  • Concentration
    0.55 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID158
  • Target name
    ADSL
  • Target description
    adenylosuccinate lyase
  • Target synonyms
    adenylosuccinase; adenylosuccinate lyase; AMPS; ASASE; ASL
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP30566
  • Protein Name
    Adenylosuccinate lyase
  • Scientific Description
    Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Canine, Human, Monkey, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism. Zhou Q et al., 2020 Aug 3, J Exp Med
    Read more
  • UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism. Feng X et al., 2020 Mar 2, EMBO J
    Read more