AF647 Anti-Mouse CD127/IL-7RA Antibody

Reddot Biotech

AF647 Anti-Mouse CD127/IL-7RA Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

A7R34

0.5 mg/ml

AlexaFluor 647

Il7r

interleukin 7 receptor

CD127; IL-; IL-7 receptor alpha chain; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7RA; IL-7Ralpha; IL-7R-alpha; interleukin 7 receptor alpha chain; interleukin-7 receptor subunit alpha

Rat

IgG2a

CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor Oe+/- chain or IL-7ROe+/-. It forms a heterodimer with the common Oe≥ chain (Oe≥c or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

Mouse

2°C to 8°C

12352203