Agomelatine [138112-76-2]

MedChem Express

Agomelatine [138112-76-2]

10

138112-76-2

Research Use Only

99.88

C15H17NO2

243.30

Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively[1]. Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively[2].

CC(NCCC1=C2C=C(OC)C=CC2=CC=C1)=O

-20°C,2°C to 8°C

12352200