Agomelatine [138112-76-2]

AbMole BioScience

Agomelatine [138112-76-2]

7

138112-76-2

Research Use Only

99.93%

C15H17NO2

243.3

Agomelatine is a metabolically stable analog of melatonin that displays agonist activity for MT1 and MT2 binding with nanomolar affinity. Agomelatine is also a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively.

COC1=CC2=C(CCNC(C)=O)C=CC=C2C=C1

-20°C

12161500