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Aha1 Antibody (OASE00110)

OASE00110
Aviva Systems Biology
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
TargetAhsa1
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Overview

  • Supplier
    Aviva Systems Biology
  • Product Name
    Aha1 Antibody (OASE00110)
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    25F2.D10
  • Concentration
    1.59 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID217737
  • Target name
    Ahsa1
  • Target description
    AHA1, activator of heat shock protein ATPase 1
  • Target synonyms
    p38, activator of 90 kDa heat shock protein ATPase homolog 1, AHA1, activator of heat shock 90kDa protein ATPase homolog 1, AHA1, activator of heat shock protein ATPase homolog 1
  • Host
    Rat
  • Isotype
    IgG2a
  • Scientific Description
    Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203