
AHR antibody detects AHR protein at cytoplasm on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human lung carcinoma. AHR antibody (GTX129012) diluted at 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
AHR antibody
GTX129012
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetAHR
Overview
- SupplierGeneTex
- Product NameAHR antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID196
- Target nameAHR
- Target descriptionaryl hydrocarbon receptor
- Target synonymsFVH3, RP85, bHLHe76, aryl hydrocarbon receptor, AH-receptor, ah receptor, aromatic hydrocarbon receptor, class E basic helix-loop-helix protein 76
- HostRabbit
- IsotypeIgG
- Protein IDP35869
- Protein NameAryl hydrocarbon receptor
- Scientific DescriptionThis gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wang TH, Huang KY, Chen CC, et al. PM2.5 promotes lung cancer progression through activation of the AhR-TMPRSS2-IL18 pathway. EMBO Mol Med. 2023,15(6):e17014. doi: 10.15252/emmm.202217014Read this paper
- Chen CS, Gao GL, Ho DR, et al. Cyproterone acetate acts as a disruptor of the aryl hydrocarbon receptor. Sci Rep. 2021,11(1):5457. doi: 10.1038/s41598-021-84769-7Read this paper
- Wang HC, Liu KY, Wang LT, et al. Aryl hydrocarbon receptor promotes lipid droplet biogenesis and metabolic shift in respiratory Club cells. Hum Cell. 2021,34(3):785-799. doi: 10.1007/s13577-021-00491-6Read this paper





![Wild-type (WT) and AHR knockout (KO) HeLa cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with AHR antibody [HL1983] (GTX637884) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637884/GTX637884_T-44872_20221209_WB_KO_watermark_22121123_584.webp)
![Wild-type (WT) and AHR knockout (KO) HeLa cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with AHR antibody [HL1984] (GTX637885) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637885/GTX637885_T-44872_20221209_WB_KO_watermark_22121123_486.webp)


