WB analysis of HEK293 cell lysates untransfected (Lane 3) and transfected with human AIRE (lane 4) using GTX89336 AIRE (isoform 1) antibody, Internal. Dilution : 0.05microg/ml
WB analysis of HEK293 cell lysates untransfected (Lane 3) and transfected with human AIRE (lane 4) using GTX89336 AIRE (isoform 1) antibody, Internal. Dilution : 0.05microg/ml
AIRE (isoform 1) antibody, Internal
GTX89336
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Porcine
TargetAIRE
Overview
- SupplierGeneTex
- Product NameAIRE (isoform 1) antibody, Internal
- Delivery Days Customer7
- Antibody SpecificityThis antibody is expected to recognise isoform 1 (NP_000374.1) only.
- Application Supplier NoteWB: 0.5-1microg/ml. IHC-P: 2.5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID326
- Target nameAIRE
- Target descriptionautoimmune regulator
- Target synonymsAIRE1; APECED; APS1; APSI; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune regulator; PGA1
- HostGoat
- IsotypeIgG
- Protein IDO43918
- Protein NameAutoimmune regulator
- Scientific DescriptionThis gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- ReactivityHuman, Porcine
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203