AKAP12 antibody [C3], C-term

GeneTex

AKAP12 antibody [C3], C-term

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.21 mg/ml

Unconjugated

AKAP12

A-kinase anchoring protein 12

A kinase (PRKA) anchor protein 12; AKAP 250; AKAP250; A-kinase anchor protein 12; A-kinase anchor protein, 250kDa; kinase scaffold protein gravin; myasthenia gravis autoantigen gravin; Src-Suppressed C Kinase Substrate; SSeCKS

Rabbit

IgG

A-kinase anchor protein 12

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203