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IHC-P analysis of human lung carcinoma tissue using GTX50128 AKT (phospho Ser473) antibody.
IHC-P analysis of human lung carcinoma tissue using GTX50128 AKT (phospho Ser473) antibody.
IHC-P analysis of human lung carcinoma tissue using GTX50128 AKT (phospho Ser473) antibody.

AKT (phospho Ser473) antibody

GTX50128
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetAKT1
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Overview

  • Supplier
    GeneTex
  • Product Name
    AKT (phospho Ser473) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID207
  • Target name
    AKT1
  • Target description
    AKT serine/threonine kinase 1
  • Target synonyms
    AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, AKT1m, PKB alpha, RAC-PK-alpha, protein kinase B alpha, proto-oncogene c-Akt, rac protein kinase alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP31749
  • Protein Name
    RAC-alpha serine/threonine-protein kinase
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lopez-Toledo G, Silva-Lucero MD, Herrera-Díaz J, et al. Patient-Derived Fibroblasts With Presenilin-1 Mutations, That Model Aspects of Alzheimer's Disease Pathology, Constitute a Potential Object for Early Diagnosis. Front Aging Neurosci. 2022,14:921573. doi: 10.3389/fnagi.2022.921573
    Read this paper
  • Chen ZH, Yan SM, Chen XX, et al. The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma. Genome Med. 2021,13(1):146. doi: 10.1186/s13073-021-00963-2
    Read this paper
  • Pan CH, Chen SY, Wang JY, et al. Sclareol ameliorated ERCC1-mediated cisplatin resistance in A549 human lung adenocarcinoma cells and a murine xenograft tumor model by suppressing AKT-GSK3β-AP1/Snail and JNK-AP1 pathways. Chem Biol Interact. 2020,332:109304. doi: 10.1016/j.cbi.2020.109304
    Read this paper
  • Pan CH, Chen CJ, Shih CM, et al. Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta. Aging (Albany NY). 2019,11(19):8085-8102. doi: 10.18632/aging.102270
    Read this paper
  • Cheng YM, Lin PL, Wu DW, et al. PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2. Oncotarget. 2018,9(41):26342-26352. doi: 10.18632/oncotarget.25254
    Read this paper
  • Zhao J, Bian C, Liu M, et al. Orchiectomy and letrozole differentially regulate synaptic plasticity and spatial memory in a manner that is mediated by SRC-1 in the hippocampus of male mice. J Steroid Biochem Mol Biol. 2018,178:354-368. doi: 10.1016/j.jsbmb.2018.02.007
    Read this paper
  • Lin PL, Chang JT, Wu DW, et al. Cytoplasmic localization of Nrf2 promotes colorectal cancer with more aggressive tumors via upregulation of PSMD4. Free Radic Biol Med. 2016,95:121-32. doi: 10.1016/j.freeradbiomed.2016.03.014
    Read this paper