IHC-P analysis of human brain tissue using GTX81701 ALAD antibody, C-term.
IHC-P analysis of human brain tissue using GTX81701 ALAD antibody, C-term.
ALAD antibody, C-term
GTX81701
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetALAD
Overview
- SupplierGeneTex
- Product NameALAD antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. IHC-P: 1:50-1:100. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID210
- Target nameALAD
- Target descriptionaminolevulinate dehydratase
- Target synonymsALADH; aminolevulinate, delta-, dehydratase; delta-aminolevulinic acid dehydratase; PBGS; porphobilinogen synthase; testicular tissue protein Li 95
- HostRabbit
- IsotypeIgG
- Protein IDP13716
- Protein NameDelta-aminolevulinic acid dehydratase
- Scientific DescriptionThe ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Ast T et al., 2019 May 30, CellRead more