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ALDH1A3 antibody [N2C2], Internal

Name: ALDH1A3 antibody [N2C2], Internal
SKU: GTX110784_G10
Availability: BackOrder

GTX110784

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetALDH1A3

Overview

Supplier
GeneTex
Product Name
ALDH1A3 antibody [N2C2], Internal
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.1 mg/ml
Conjugate
Unconjugated
Gene ID220
Target name
ALDH1A3
Target description
aldehyde dehydrogenase 1 family member A3
Target synonyms
ALDH1A6, ALDH6, MCOP8, RALDH3, retinaldehyde dehydrogenase 3, acetaldehyde dehydrogenase 6, aldehyde dehydrogenase 6
Host
Rabbit
Isotype
IgG
Protein IDP47895
Protein Name
Retinaldehyde dehydrogenase 3
Scientific Description
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or cellular retinol-binding protein form. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Chung SY, Hung YP, Pan YR, et al. Ruxolitinib Combined with Gemcitabine against Cholangiocarcinoma Growth via the JAK2/STAT1/3/ALDH1A3 Pathway. Biomedicines. 2021,9(8). doi: 10.3390/biomedicines9080885
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Park JW, Jung KH, Byun Y, et al. ATP-binding Cassette Transporters Substantially Reduce Estimates of ALDH-positive Cancer Cells based on Aldefluor and AldeRed588 Assays. Sci Rep. 2019,9(1):6462. doi: 10.1038/s41598-019-42954-9
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Chen MH, Weng JJ, Cheng CT, et al. ALDH1A3, the Major Aldehyde Dehydrogenase Isoform in Human Cholangiocarcinoma Cells, Affects Prognosis and Gemcitabine Resistance in Cholangiocarcinoma Patients. Clin Cancer Res. 2016,22(16):4225-35. doi: 10.1158/1078-0432.CCR-15-1800
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