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Alofanib [1612888-66-0]

Alofanib [1612888-66-0]

T5122
TargetMol Chemicals
CAS Number1612888-66-0
DownloadMSDS
Product group Chemicals
Estimated Purity98.82%
Molecular Weight413.4
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Alofanib [1612888-66-0]
  • Delivery Days Customer
    9
  • CAS Number
    1612888-66-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Alofanib
  • Estimated Purity
    98.82%
  • Molecular Formula
    C19H15N3O6S
  • Molecular Weight
    413.4
  • Scientific Description
    Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM). It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1cc(c(NS(=O)(=O)c2cccc(c2)C(O)=O)cc1-c1cccnc1)[N+]([O-])=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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