Alofanib (RPT835)

AbMole BioScience

Alofanib (RPT835)

9

1612888-66-0

Research Use Only

C19H15N3O6S

413.40

Alofanib (RPT835) is a novel selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells.

CC1=CC(=C(N[S](=O)(=O)C2=CC=CC(=C2)C(O)=O)C=C1C3=CC=CN=C3)[N+]([O-])=O

12352200