Alpelisib

MedChem Express

Alpelisib [1217486-61-7]

10

1217486-61-7

Research Use Only

99.95

C19H22F3N5O2S

441.47

Alpelisib (BYL-719) is a potent, selective, and orally active PI3Kalpha inhibitor. Alpelisib (BYL-719) shows efficacy in targeting PIK3CA-mutated cancer. Alpelisib (BYL-719) also inhibits p110alpha/p110gamma/p110delta/p110beta with IC 50 s of 5/250/290/1200 nM, respectively. Antineoplastic activity [1] [2] [3] .

CC(N=C(S1)NC(N2CCC[C@H]2C(N)=O)=O)=C1C3=CC(C(C)(C(F)(F)F)C)=NC=C3

-20°C,2°C to 8°C

12352200