WB analysis of HEK293T (A), A375 (B), LO2 (C), PC12 (D) whole cell lysates using GTX54918 alpha 2 Macroglobulin antibody.
WB analysis of HEK293T (A), A375 (B), LO2 (C), PC12 (D) whole cell lysates using GTX54918 alpha 2 Macroglobulin antibody.
alpha 2 Macroglobulin antibody
GTX54918
Overview
- SupplierGeneTex
- Product Namealpha 2 Macroglobulin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2
- Target nameA2M
- Target descriptionalpha-2-macroglobulin
- Target synonymsA2MD; alpha-2-M; alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; FWP007; S863-7
- HostRabbit
- IsotypeIgG
- Protein IDP01023
- Protein NameAlpha-2-macroglobulin
- Scientific DescriptionThe protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimers disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203