alpha-Cortolone

Biorbyt

alpha-Cortolone [516-42-7]

10

516-42-7

Research Use Only

98.00%

C21H34O5

366.49

alpha-Cortolone, a metabolite of the glucocorticoid cortisol (hydrocortisone), is produced through the action of 20alpha-hydroxysteroid dehydrogenase (20alpha-HSD) via a tetrahydrocortisone (THE) intermediate. Studies indicate that urinary levels of alpha-cortolone are reduced in patients experiencing severe anorexia nervosa and postmenopausal women diagnosed with endometrial adenocarcinoma, in comparison to postmenopausal women without the condition.

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-20°C

12352200