alpha-Cortolone [516-42-7]

TargetMol Chemicals

alpha-Cortolone [516-42-7]

16

516-42-7

Chemical

Research Use Only

alfa-Cortolone

C21H34O5

366.49

alpha-Cortolone, a metabolite of the glucocorticoid cortisol (hydrocortisone), is produced through the action of 20alpha-hydroxysteroid dehydrogenase (20alpha-HSD) via a tetrahydrocortisone (THE) intermediate. Studies indicate that urinary levels of alpha-cortolone are reduced in patients experiencing severe anorexia nervosa and postmenopausal women diagnosed with endometrial adenocarcinoma, in comparison to postmenopausal women without the condition.

3 years

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C(=O)C1)[H])[H])(CC[C@@]2([C@H](CO)O)O)[H]

-20°C

12352200