alpha Fodrin antibody [D8B7]

GeneTex

alpha Fodrin antibody [D8B7]

9

Clone D8B7 is developed against the alpha II spectrin SH3 domain (Xu et al., 2001). Clone D8B7 is a specific marker for human, rat and mouse alpha II spectrin or fodrin. In cerebellar cell cultures, it labelsaxons and periphery of cell bodies consistent w

ELISA: Use at a dilution of 1/10^5-1/10^6IF: Use at a dilution of 1/100 - 1/500. IHC-Fr: Use at a dilution of 1/50 - 1/100. WB: Use at a dilution of 1/10^2-1/10^3. Predicted molecular weight: 297 kDa. Optimal dilutions/concentrations should be determined by the end user.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

D8B7

Unconjugated

SPTAN1

spectrin alpha, non-erythrocytic 1

alpha-fodrin; alpha-II spectrin; DEE5; EIEE5; epididymis secretory sperm binding protein; fodrin alpha chain; NEAS; spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; SPTA2

Mouse

IgG2b

Spectrin alpha chain, non-erythrocytic 1

Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]

Human

-20°C or -80°C,2°C to 8°C

12352203