alpha-Galactosylceramide (Dansylated)

AdipoGen Life Sciences

alpha-Galactosylceramide (Dansylated)

10

Research Use Only

>95%

C62H111N3O10S

1090.6

Chemical. CAS: 424823-23-4. Formula: C62H111N3O10S. MW: 1090.6. . Fluorescent alpha-GalCer derivative. Potent stimulator of invariant natural killer T (iNKT) cells similar to alpha-GalCer (determined by CD86 expression in DCs and B cells, and IL-2 production by iNKT cells). Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells. Used as a fluorescent marker for the uptake of the glycolipid by dendritic cells (DCs) in vitro and to better understand the mechanism of iNKT cell activation. - Fluorescent alpha-GalCer derivative. Potent stimulator of invariant natural killer T (iNKT) cells similar to alpha-GalCer (determined by CD86 expression in DCs and B cells, and IL-2 production by iNKT cells). Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells. Used as a fluorescent marker for the uptake of the glycolipid by dendritic cells (DCs) in vitro and to better understand the mechanism of iNKT cell activation.

O[C@H]1[C@@H](O)[C@@H](CNS(C2=CC=CC3=C2C=CC=C3N(C)C)(=O)=O)O[C@H](OC[C@@H]([C@@H]([C@@H](CCCCCCCCCCCCCC)O)O)NC(CCCCCCCCCCCCCCCCCCCCCCCCC)=O)[C@@H]1O

-20°C,2°C to 8°C

12352200