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Chemical Structure
Chemical Structure
Chemical Structure

Asialo-GM2 [35960-33-9]

Research Use Only
AG-CN2-9009
AdipoGen Life Sciences
CAS Number35960-33-9
Product group Chemicals
Estimated Purity>98%
Molecular Weight1093.4 (calculated on sphingosine C18:1 and stearic acid)
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Asialo-GM2
  • Delivery Days Customer
    10
  • CAS Number
    35960-33-9
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C56H104N2O18
  • Molecular Weight
    1093.4 (calculated on sphingosine C18:1 and stearic acid)
  • Scientific Description
    Chemical. CAS: 35960-33-9. Formula: C56H104N2O18. MW: 1093.4 (calculated on sphingosine C18:1 and stearic acid). Semisynthetic. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Asialo-ganglioside GM2 is a major neural ganglioside in Tay Sachs and Sandhoff diseases. - Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Asialo-ganglioside GM2 is a major neural ganglioside in Tay Sachs and Sandhoff diseases.
  • SMILES
    [H][C@@](CO[C@@H]1O[C@@H](CO)[C@@H](O[C@@H]2OC(CO)[C@H](O[C@H]3O[C@@H](CO)[C@H](O)C(O)C3NC(C)=O)[C@H](O)C2O)C(O)C1O)(NC(=O)CCCCCCCCCCCCCCCCC)[C@]([H])(O)\C=C\CCCCCCCCCCCCC
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Role of membrane gangliosides in the binding and action of bacterial toxins: P.H. Fishman; J. Membr. Biol. 69, 85 (1982)