![IHC-P analysis of human leiomyoma tissue using GTX18147 alpha Smooth Muscle Actin antibody [0.N.5]. IHC-P analysis of human leiomyoma tissue using GTX18147 alpha Smooth Muscle Actin antibody [0.N.5].](https://www.genetex.com/upload/website/prouct_img/normal/GTX18147/GTX18147_20191203_IHC-P_28_w_23060620_330.webp)
IHC-P analysis of human leiomyoma tissue using GTX18147 alpha Smooth Muscle Actin antibody [0.N.5].
alpha Smooth Muscle Actin antibody [0.N.5]
![Research Use Only](static/images/certificates/ruo.jpg)
GTX18147
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rabbit
TargetACTA2
Overview
- SupplierGeneTex
- Product Namealpha Smooth Muscle Actin antibody [0.N.5]
- Delivery Days Customer9
- Antibody SpecificityRecognizes human alpha-smooth muscle isoform of actin. Stains smooth muscle cells in vessel walls, gut wall and myometrium. Myoepithelial cells in breast and salivary gland are also stained. Reacts with tumors arising from smooth muscles and myoepithelial
- Application Supplier NoteIHC-P: 1:800 for 20 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID0.N.5
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID59
- Target nameACTA2
- Target descriptionactin alpha 2, smooth muscle
- Target synonymsactin, alpha 2, smooth muscle, aorta; actin, aortic smooth muscle; ACTSA; alpha-cardiac actin; cell growth-inhibiting gene 46 protein
- HostMouse
- IsotypeIgG2a
- Protein IDP62736
- Protein NameActin, aortic smooth muscle
- Scientific DescriptionThis gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
- ReactivityHuman, Mouse, Rabbit
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Photooxidation and Pentagalloyl Glucose Cross-Linking Improves the Performance of Decellularized Small-Diameter Vascular Xenograft In Vivo. Liu Y et al., 2022, Front Bioeng BiotechnolRead more
- CD8+ T cells target cerebrovasculature in children with cerebral malaria. Riggle BA et al., 2020 Mar 2, J Clin InvestRead more
- Use of a murine endometriosis interna model for the characterization of compounds that effectively treat human endometriosis. Otto C et al., 2012 Mar, Exp Ther MedRead more
- Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells. Klarquist J et al., 2009 Dec, Am J PatholRead more