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alpha Smooth Muscle Actin antibody [0.N.5]

Name: alpha Smooth Muscle Actin antibody [0.N.5]
SKU: GTX18147_G10
Availability: BackOrder

GTX18147

ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rabbit

TargetACTA2

Overview

Supplier
GeneTex
Product Name
alpha Smooth Muscle Actin antibody [0.N.5]
Delivery Days Customer
9
Application Supplier Note
IHC-P: 1:800 for 20 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
0.N.5
Conjugate
Unconjugated
Gene ID59
Target name
ACTA2
Target description
actin alpha 2, smooth muscle
Target synonyms
ACTSA, SMDYS, actin, aortic smooth muscle, actin, alpha 2, smooth muscle, aorta, alpha-cardiac actin, cell growth-inhibiting gene 46 protein
Host
Mouse
Isotype
IgG2a
Protein IDP62736
Protein Name
Actin, aortic smooth muscle
Scientific Description
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
Reactivity
Human, Mouse, Rabbit
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Xie X, Wu Q, Liu Y, et al. Vascular endothelial growth factor attenuates neointimal hyperplasia of decellularized small-diameter vascular grafts by modulating the local inflammatory response. Front Bioeng Biotechnol. 2022,10:1066266. doi: 10.3389/fbioe.2022.1066266
Read this paper
Chen C, Lu T, Wu Z, et al. A proteomics analysis of neointima formation on decellularized vascular grafts reveals regenerative alterations in protein signature running head: Proteomics analysis of neointima formation. Front Bioeng Biotechnol. 2022,10:894956. doi: 10.3389/fbioe.2022.894956
Read this paper
Taghizadeh H, Taghizadehghalehjoughi A, Yildirim S, et al. Deteriorated Vascular Homeostasis in Hypertension: Experimental Evidence from Aorta, Brain, and Pancreatic Vasculature. J Pers Med. 2022,12(10). doi: 10.3390/jpm12101602
Read this paper
Liu Y, Chen C, Xie X, et al. Photooxidation and Pentagalloyl Glucose Cross-Linking Improves the Performance of Decellularized Small-Diameter Vascular Xenograft In Vivo. Front Bioeng Biotechnol. 2022,10:816513. doi: 10.3389/fbioe.2022.816513
Read this paper
Riggle BA, Manglani M, Maric D, et al. CD8+ T cells target cerebrovasculature in children with cerebral malaria. J Clin Invest. 2020,130(3):1128-1138. doi: 10.1172/JCI133474
Read this paper
Otto C, Schkoldow J, Krahl E, et al. Use of a murine endometriosis interna model for the characterization of compounds that effectively treat human endometriosis. Exp Ther Med. 2012,3(3):410-414.
Read this paper
Klarquist J, Barfuss A, Kandala S, et al. Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells. Am J Pathol. 2009,175(6):2463-72. doi: 10.2353/ajpath.2009.090525
Read this paper

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alpha Smooth Muscle Actin antibody [0.N.5]

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Overview

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