IHC-P analysis of human brain, Lewy body dementia using GTX01946 alpha Synuclein antibody [KM51]. Note staining of alpha-synuclein-containing Lewy bodies.
IHC-P analysis of human brain, Lewy body dementia using GTX01946 alpha Synuclein antibody [KM51]. Note staining of alpha-synuclein-containing Lewy bodies.
alpha Synuclein antibody [KM51]
GTX01946
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSNCA
Overview
- SupplierGeneTex
- Product Namealpha Synuclein antibody [KM51]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:20-1:40. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDKM51
- ConjugateUnconjugated
- Gene ID6622
- Target nameSNCA
- Target descriptionsynuclein alpha
- Target synonymsNACP, PARK1, PARK4, PD1, alpha-synuclein, I+/--synuclein, non A-beta component of AD amyloid, synuclein alpha-140, synuclein, alpha (non A4 component of amyloid precursor)
- HostMouse
- IsotypeIgG1
- Protein IDP37840
- Protein NameAlpha-synuclein
- Scientific DescriptionAlpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimers disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
Datasheet
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