AMACR antibody

GeneTex

AMACR antibody

9

WB: 1:500. ICC/IF: 1:100. IP: 1:200. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

AMACR

alpha-methylacyl-CoA racemase

2-methylacyl-CoA racemase; alpha-methylacyl-CoA racemase; AMACRD; CBAS4; P504S; RACE; RM

Rabbit

IgG

Alpha-methylacyl-CoA racemase

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]

Human, Rat

-20°C or -80°C,2°C to 8°C

12352203