IHC-P analysis of human prostatic adenocarcinoma using GTX01883 AMACR antibody [EPMU1]. Note the characteristic granular cytoplasmic staining of malignant cells.
IHC-P analysis of human prostatic adenocarcinoma using GTX01883 AMACR antibody [EPMU1]. Note the characteristic granular cytoplasmic staining of malignant cells.
AMACR antibody [EPMU1]
GTX01883
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetAMACR
Overview
- SupplierGeneTex
- Product NameAMACR antibody [EPMU1]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDEPMU1
- ConjugateUnconjugated
- Gene ID23600
- Target nameAMACR
- Target descriptionalpha-methylacyl-CoA racemase
- Target synonyms2-methylacyl-CoA racemase; alpha-methylacyl-CoA racemase; AMACRD; CBAS4; P504S; RACE; RM
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203