(+/-)-AMG 487 [947536-03-0]
HY-15319A
CAS Number947536-03-0
Product group Chemicals
Molecular Weight603.59
Overview
- SupplierMedChem Express
- Product Name(+/-)-AMG 487 [947536-03-0]
- Delivery Days Customer10
- CAS Number947536-03-0
- CertificationResearch Use Only
- Molecular FormulaC32H28F3N5O4
- Molecular Weight603.59
- Scientific Description(+/-)-AMG 487 is a racemate of AMG 487. AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively[1].
- SMILESO=C(N(C(C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5
- UNSPSC12352200
