(+/-)-AMG 487

TargetMol Chemicals

(±)-AMG 487

9

Chemical

Research Use Only

(±)-AMG 487

C32H28F3N5O4

603.59

AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively).

3 years

CCOC1=CC=C(N2C(C(N(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC4=CN=CC=C4)C)=NC5=C(C2=O)C=CC=N5)C=C1

-20°C

12352200