AMI-1 (free acid) [134-47-4]

MedChem Express

AMI-1 (free acid) [134-47-4]

9

134-47-4

Research Use Only

99.70

C21H16N2O9S2

504.49

AMI-1 free acid is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 microM and 3.0 microM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 free acid exerts PRMTs inhibitory effects by blocking peptide-substrate binding[1].

O=C(NC1=CC2=CC(S(=O)(O)=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)(O)=O)=CC(O)=C4C=C3

2°C to 8°C,-20°C

12352200