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AMI-1 (free acid)

HY-18962A
MedChem Express
CAS Number134-47-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.70
Molecular Weight504.49
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AMI-1 (free acid) [134-47-4]
  • Delivery Days Customer
    9
  • CAS Number
    134-47-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.70
  • Molecular Formula
    C21H16N2O9S2
  • Molecular Weight
    504.49
  • Scientific Description
    AMI-1 free acid is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs) , with IC 50 s of 8.8 microM and 3.0 microM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 free acid exerts PRMTs inhibitory effects by blocking peptide-substrate binding [1] .
  • SMILES
    O=C(NC1=CC2=CC(S(=O)(O)=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)(O)=O)=CC(O)=C4C=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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