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AMI-1 free acid

ORB1905872
Biorbyt
CAS Number134-47-4
Product group Chemicals
Estimated Purity97.80%
Molecular Weight504.49
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Overview

  • Supplier
    Biorbyt
  • Product Name
    AMI-1 free acid [134-47-4]
  • Delivery Days Customer
    10
  • CAS Number
    134-47-4
  • Certification
    Research Use Only
  • Estimated Purity
    97.80%
  • Molecular Formula
    C21H16N2O9S2
  • Molecular Weight
    504.49
  • Scientific Description
    AMI-1 free acid is a potent, cell-permeable, and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with inhibitory concentration 50 (IC50) values of 8.8 microM for human PRMT1 and 3.0 microM for yeast-Hmt1p. It achieves its PRMTs inhibitory activity by obstructing peptide-substrate binding [1].
  • SMILES
    O=C(NC=1C=CC2=C(O)C=C(C=C2C1)S(=O)(=O)O)NC=3C=CC4=C(O)C=C(C=C4C3)S(=O)(=O)O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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