Amorfrutin A [80489-90-3]

MedChem Express

Amorfrutin A [80489-90-3]

5

80489-90-3

Research Use Only

C21H24O4

340.41

Amorfrutin A is the inhibition of NF-kappaB activation, that inhibits TNF-alpha-induced IkappaBalpha degradation, p65 nuclear translocation, and DNA-binding activity. Amorfrutin A promotes TNF-alpha-induced apoptosis in HeLa cell through promotion of caspase-3 and PARP proteolysis[1].

O=C(O)C1=C(CCC2=CC=CC=C2)C=C(OC)C(C/C=C(C)\C)=C1O

12352200