Amsilarotene [125973-56-0]

TargetMol Chemicals

Amsilarotene [125973-56-0]

4

125973-56-0

Chemical

Research Use Only

Amsilarotene

99.27%

C20H27NO3Si2

385.6

Amsilarotene (TAC101) inhibits the phosphorylation of retinoblastoma gene product (RB) and increases the presence of 2 cyclin-dependent kinases (CDK) inhibitors resulting in cell cycle arrest. This agent also causes a cytotoxic decline in the thymidylate synthase and cyclin A expression.

3 years

C[Si](C)(C)c1cc(cc(c1)[Si](C)(C)C)C(=O)Nc1ccc(cc1)C(O)=O

-20°C

12352200