
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA168510(ANLN Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
ANLN Antibody
CSB-PA168510
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetANLN
Overview
- SupplierCusabio
- Product NameANLN Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID54443
- Target nameANLN
- Target descriptionanillin actin binding protein
- Target synonymsanillin; FSGS8; scra; Scraps
- HostRabbit
- IsotypeIgG
- Protein IDQ9NQW6
- Protein NameAnillin
- Scientific DescriptionAnillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203