anti-ABCG2 antibody

Arigo Biolaboratories

anti-ABCG2 antibody

23

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

Abcg2

ATP binding cassette subfamily G member 2 (Junior blood group)

ABC15, ABCP, BCRP, Bcrp1, MXR, MXR1, broad substrate specificity ATP-binding cassette transporter ABCG2, ATP-binding cassette sub-family G member 2, ATP-binding cassette, sub-family G (WHITE), member 2, breast cancer resistance protein 1 homolog, mitoxantrone resistance protein 1, urate exporter

Rabbit

IgG

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Mouse

-20°C

12352203