Western blot analysis using anti-ACE2 (human), mAb (AC384) (Biotin) (Prod. No. AG-20A-0037B) at 1:2000 dilution.1: Human ACE2 Fc-fusion protein.2: Human ACE2 (Ecto domain) (FLAG®-tagged) 3: HepG2 cell lysate.4: Other Fc
Western blot analysis using anti-ACE2 (human), mAb (AC384) (Biotin) (Prod. No. AG-20A-0037B) at 1:2000 dilution.1: Human ACE2 Fc-fusion protein.2: Human ACE2 (Ecto domain) (FLAG®-tagged) 3: HepG2 cell lysate.4: Other Fc
anti-ACE2 (human), mAb (AC384) (Biotin)
AG-20A-0037B
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetACE2
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-ACE2 (human), mAb (AC384) (Biotin)
- Delivery Days Customer10
- Antibody SpecificityRecognizes human ACE2.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAC384
- Concentration1 mg/ml
- ConjugateBiotin
- FormulationLiquid
- Gene ID59272
- Target nameACE2
- Target descriptionangiotensin converting enzyme 2
- Target synonymsACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; angiotensin-converting enzyme 2; angiotensin-converting enzyme homolog; angiotensin-converting enzyme-related carboxypeptidase; metalloprotease MPROT15; peptidyl-dipeptidase A; truncated angiotensin converting enzyme 2
- HostMouse
- IsotypeIgG1
- Protein IDQ9BYF1
- Protein NameAngiotensin-converting enzyme 2
- Scientific DescriptionAngiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating peptides. ACE2 has approximately 42% sequence identity with ACE, and its cytoplasmic and transmembrane domains show 48% homology to the protein collectrin that plays a critical role in the amino acid absorption of the kidney. ACE2 converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. ACE2 is involved in the regulation of systemic blood pressure and has direct effects on cardiac functions. It is expressed predominantly in endothelial cells of the lung, gut, heart and kidney. ACE2 together with the protease TMPRSS2 acts as a functional receptor for SARS coronavirus as well as for the new highly pathogenic coronavirus, 2019-nCoV/SARS-CoV-2, which is cause for pneumonia COVID-19. - Monoclonal Antibody. Recognizes human ACE2. Isotype: Mouse IgG1kappa. Clone: AC384. Applications: ELISA, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203