Anti-BA46 [Mc3]

Absolute Antibody

Anti-BA46 [Mc3]

9

BA46 is a glycoprotein of the human milk fat globule membrane, and is also expressed in breast carcinomas.

In radioimmunoassays Mc3 bound to membranes of HMFG, MCF-7, MDA-MB- 157, SKBR-3, and BT-20 cells but not breast fibroblast, Hela, HT-29, Bristol 8, Hs294T, Hs695T, Hs785T, Hs769T, A498, PANC-1, MIA PaCa-2 or A-549 cells (Ceriani et al, 1983). Human Mc3 was characterised using biodistribution studies and shown to have similar properties to the murine Mc3 (Couto et al, 1995).

RadioImmunoAssay

Research Use Only

Monoclonal

Mc3

MFGE8

milk fat globule EGF and factor V/VIII domain containing

BA46; breast epithelial antigen BA46; EDIL1; HMFG; hP47; HsT19888; lactadherin; medin; MFG-E8; MFGM; milk fat globule-EGF factor 8 protein; O-acetyl disialoganglioside synthase; OAcGD3S; SED1; SPAG10; sperm associated antigen 10; sperm surface protein hP47

Human

IgG1

Lactadherin

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203